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Their hydrophobic surfaces (shown in orange) bind to the lipid core of the bilayer, and their hydrophilic surfaces (shown in blue) form cylindrical pores, disrupting the membrane integrity

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These challenges highlight a need for new research aimed at better understanding TBI pathogenesis and identifying specific biomarkers corresponding to underlying cellular, structural and secretomic changes that can improve clinical decision making

CGA knockout also inhibited the proliferation of MDR cells exposed to chemotherapy (Figure 2B and Supplemental Figure 2E)