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Improvements in cardiovascular risk markers, including cholesterol, triglycerides, and blood pressure, were also observed

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3 Oxidative stress and endothelium damage 3.1 Oxidative stress is a multicompartmental phenomenon originating from different sources Oxidative stress occurs when there is large-scale production of ROS and/or an underperforming antioxidant system

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Hepcidin, the master regulator of iron egress, may further refine risk stratification, as low hepcidin levels have been associated with a higher incidence of HF and mortality, potentially reflecting a state of functional iron deficiency [227, 387]