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doi: 10.1016/j.redox.2019.101378 252 SelkoeDJ

PMC 5009355

however, there are some indications provided by in vitro assays with pharmacological inhibitors and silencing approaches, suggesting that this enzyme can be critical for cancer cell proliferation, bioenergetics, and cell signaling (125)

This impairs homologous recombination (HR)-mediated DNA repair, thereby contributing to carcinogenesis

4.7 years)

Additionally, SB treatment suppressed the production of inflammatory markers IL-1 and chemokine CXCL10, and blocked ischemia-elicited upregulation of COX-2 [17, 18]