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Functional significance of eIF5A and its hypusine modification in eukaryotes

The pathogenesis of neurodegenerative diseases has several common features, such as oxidative damage and mitochondrial dysfunction

doi: 10.1038/ncb2432 13 CramerSLSahaALiuJTadiSTizianiSYanWet al

Even in conditional GPX4 knockout mouse models, excessive lipid peroxidation and oxidative stresses were detrimental to tissues [28,29,30,31]

PMID: 7 SosaGCrosswhiteBKirschnerA

The repeated occurrence of epidemic and pandemic events has profound consequences, contributing to increased mortality, disrupting economies, and hindering sustainable development