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The innate immune system recognizes the conserved structures of pathogens via a series of pattern recognition receptors (PRRs), prompting immune cells to respond and secrete inflammatory cytokines (Rock et al., 2010

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In: KoletzkoBet al, editors

Along with oxidative stress, these abnormal molecular changes lead to impaired mitochondrial respiratory function, ATP depletion, and various destructive cellular processes, such as mitochondrial fission, mitophagy, and programmed cell death, as we discuss below

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The low-specificity L-threonine aldolase LtaE, which cleaves several L-3-hydroxy--amino acids, like HTML, to glycine and a corresponding aldehyde and which may accommodate molecules larger than L-threonine in its large substrate binding pocket ( E