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*Correspondence: Vishwanath Venketaraman, [email protected] This article was submitted to Clinical Microbiology, a section of the journal Frontiers in Cellular and Infection Microbiology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Epigeneticmetabolic crosstalk in CSCs sustains stemness and immune evasion, where metabolites act as epigenetic regulators and epigenetic programs in turn reinforce metabolic reprogramming, ultimately driving ICI resistance