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The effects observed in chronic wounds likely reflect T4's ability to address multiple pathological features of impaired healing, including excessive inflammation, inadequate angiogenesis, impaired cell migration, and unfavorable extracellular matrix composition

To further confirm metabolic competence in selected liver cell models (PHH, HepG2 cells), CYP mRNA expression was investigated by quantitative polymerase chain reaction (qRT-PCR)

Vitamin D injections are ideal for individuals with deficiencies, especially during the winter months or for those with limited sun exposure

They are not intended for human consumption , as they lack the same purity and quality controls as their medical-grade counterparts

Despite these advantages, EDS may be less suitable for patients who are unable to generate reproducible exhalation manoeuvres and may entail greater device complexity and cost than conventional pump sprays