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Considering the results of our in vitro experiments, the anti-RGMa antibody is likely to block the direct and disease-specific interaction between RGM-expressing mature neurons in the GCL and neogenin-expressing neurogenic cells, including NSCs and immature neurons

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Similarly, concentrations of DMSO ranging from 0.01-1% were reported to cause hyperactivity in zebrafish larvae, with morphological abnormalities noted only at the 1% exposure group 50

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