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Studies have shown that a higher ratio of serum cortisol to follicular cortisol was associated with pregnancy, and that infertile women had higher levels of stress in terms of circulating prolactin and cortisol compared to fertile women in the control group (190)

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The possible reason for the inconsistent findings can be explained by various factors including cancer type, drug dosage, synergism, bioavailability, patients lifestyle, tendency to take supplements, and the duration of the studies with other variables incorporated (67) (Table 7)

10.1186/s12967-018-1641-1 6 ChengB.HongX.WangL.CaoY.QinD.ZhouH.et al (2022)

Cell Signal 19 , 23612369 (2007)

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