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performed the literature searches

3B and E) with the highest SAAM score had the poorest prognosis

However, they may cause side effects like nausea, diarrhea and skin reactions in some people

Of these rare syndromes, THMD3 (also called Amish-type microcephaly or Amish lethal microcephaly) has the more severe phenotype, resulting in a congenital microcephaly, elevated concentrations of -ketoglutarate in urine, and usually death in infancy (121)