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NMR Biomed 11:266272 Edden RAE, Harris AD, Murphy K, Evans CJ, Saxena N, Hall JE, Bailey DM, Wise RG (2010) Edited MRS is sensitive to changes in lactate concentration during inspiratory hypoxia

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This design effectively tethers the intracellular degradation machinery to the inner leaflet, enabling ubiquitination and degradation of the targets intracellular domain and thereby extending PROTAC applicability to traditionally undruggable membrane proteins

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