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Further experiments in intracranial GBM xenograft mouse models demonstrated that ferroptosis leads to increased TAM infiltration and M2-type polarization

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In short, the above experiments indicate that the treatment of GSH consumption-enhanced PDT and SDT has a profound effect on retarding tumor progression

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Like ASXL1, the transcriptional co-activator bromodomain and extra-terminal domain 4 (BRD4) is also linked to tumorigenesis