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Curcumin neither inhibits the transcription of p53 mRNA nor protects tumor cells against the cytotoxic effect of cisplatin on HepG2 cells [126]

The search strategy used a combination of subject terms (such as MeSH terms) and free terms, and Boolean operators (AND/OR/NOT) were used to construct an accurate search formula

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In addition, there is an increase in the expression of IL-6, TNF-, and increased oxidative damage coupled with a reduction in antioxidant capacity (Guest et al., 2014

Building on these promising results, a phase 3 trial is currently underway, involving 200 patients over two years

Qin and colleagues designed a hydrogel system, OSPPB (Figure 8A)