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Since IL-4 plays a pivotal role in activating 12/15-LOX, a reduction in IL-4 levels leads to decreased expression of 12/15-LOX [92] (Table 1)

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doi: 10.1016/j.jff.2014.12.049 501 KumarYSinghalSTarafdarAPharandeAGanesanMBadgujarPC

Statements Author contributions JS: conceptualization, methodology, validation, formal analysis, investigation, resources, data curation, writing (original draft and review and editing), and visualization

A Multidimensional Review of Pimpinella anisum and Recommendation for Future Research to Face Adverse Climatic Conditions

Secondly, the lipid matrix of SLNs undergoes polymorphic transformations during storage, causing the lipid crystals to rearrange into a more organized lattice and gradually expel the encapsulated drug