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In mammalian systems, RAR signaling is categorized into three distinct types based on gene encoding: RAR, RAR and RAR, with RAR being the most ubiquitously expressed (56)

HIF-1, the oxygen-sensitive subunit of the HIF-1 transcriptional complex, is stabilized under hypoxic conditions and triggers a cascade of cellular responses (Koh and Powis, 2012)

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Younger age and less severe entry strokes were associated with lower IS recurrence rates, however, our results demonstrated an unmet need among all patient subgroups