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10.1038/s41598-024-64228-9 49

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Moreover, 50 mg/day of Zn supplementation for 12 weeks in obese examinees was associated with a significant more than twofold increase in serum adiponectin concentration [87]

The interplay between fluctuating estrogen levels and the heightened sensitivity of the brains anxiety circuits may explain why menopause represents a critical window of vulnerability for anxiety disorders [57,58]