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The short and highly conserved cytoplasmic domain contains seven tyrosine residues and several Ser and Thr residues, which represent potential docking sites for proteins with Src homology two domains and recognition sites for receptor tyrosine and other kinases

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Furthermore, we investigated the metabolic fate of U- 15 N glutamine in vivo by LCMS, which produces glutathione containing one 15 N atom via GSH de novo synthesis (Fig