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The investigations of the present study revealed diminished Nrf2 and HO-1 expression in HG-induced HK-2 cells in vitro and in an in vivo DN model

11201ES03, Yeasen, Shanghai, China) on a CFX384 real-time PCR system (Bio-Rad Laboratories, Hercules, CA, USA)

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In light of these changes, identifying region-specific regulatory mechanisms of mitophagy is crucial for intervening in the aging process

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