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The patients without a history of gastrectomy complained of pain in other intraoral mucosal areas (5/11, 45.5 %), dry mouth (3/11, 27.3 %), and dysgeusia (2/11, 18.2 %)

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A 2025 systematic review identified 36 studies from 1993 to 2024, including 35 preclinical studies and only 1 clinical study

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Semaglutide directly stimulates GLP-1 receptors in the brain, decreasing appetite and changing satiety signals, and has a prolonged half-life of approximately seven days, enabling once-weekly administration