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These findings suggest that targeting the JAK/STAT axis could provide a dual benefit in HS by attenuating both inflammation and fibrosis, while also addressing the contribution of adipose tissue-derived mediators to these pathogenic mechanisms (Table 2)

This was followed by a 6-week washout period

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This sets the stage for adverse effects on the body, including chronic disease and illness

Monocytes: a novel drug delivery system targeting atherosclerosis

It rapidly reacts with nucleophilic molecules such as glutathione, leading to depletion of cellular antioxidants