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November 26, 2021

The hypopigmentation associated with PIH that develops after injury, burn, or other inflammatory condition may be permanent if the melanocytes in the area have been severely damaged or destroyed

Study protocols and animal experiments performed in Zaragoza were approved by the Animal Experimentation Ethics Committee of the University of Zaragoza (numbers PI 18/2, PI 18/23, PI 62/22 and PI 24/25) and in accordance with institutional, national and European ethical animal regulations (Protection of Animals Act)

Nevertheless, in this case, refolding occurs most efficiently at the most reducing of PDI redox poises

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Lactate induces vascular permeability via disruption of VE-cadherin in endothelial cells during sepsis