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Serum chemerin in obese children and adolescents before and after L-Carnitine therapy: relation to nonalcoholic fatty liver disease and other features of metabolic syndrome

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Moreover, inflammatory form as pyroptosis, of programmed cell death, has been implicated in liver diseases, where caspase-1 activation triggers membrane rupture, inflammatory cytokine release, and exacerbated tissue damage 4 Furthermore, inflammasomes, including the NLRP3 ((NOD-, LRR-, and pyrin domain-comprising protein 3), have been concerned in liver diseases, where activation of this complex triggers caspase-1 activation, promoting pyroptosis and inflammatory cytokines release such as IL-1 and IL-18, further exacerbating liver damage 5

thaliana GSTF2 as a template (PDB code: 1GNW)