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Masisi, B

Rahmanian M

Future efforts should utilize in vitro dynamic models (such as the hollow-fiber infection model) and animal models to comprehensively understand the PK/PD properties of drugs, thereby enabling dosing regimens that provide maximal synergy while minimizing toxicity and resistance development (Wale et al., 2024)

The researchers reported increased synthesis and mRNA expression of neurogenic differentiation markers including Nestin, GAP43, Tubulin III, and Doublecortin

The neuroprotective GlyT1 inhibitors effects have been associated with a reduction in GluN2B-containing NMDA receptor expression and modulation of glycinergic and glutamatergic neurotransmission (Pinto et al