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The origin of HGF present in the tumor microenvironment is unknown and HGF could be synthesized by a variety of tissues throughout the body, such as the liver itself or by the adipose tissue

We are grateful to the Moscow State University Development Program PNR5 for providing access to the Amnis Flowsight flow cytometer and to the Olympus IX83 microscope

the D-Nle-Trp-Ile-NH(CH 2 ) 5 CONH 2 analog had intermediate inhibitory activity, and the D-Nle-Met-Ile-NH(CH 2 ) 5 CONH 2 analog showed no ability to effect on Met activation