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What the Drug Interaction Databases Say Major drug interaction databases (Lexicomp, Micromedex, Clinical Pharmacology) do not list a GHK-Cu/metformin interaction

Dont leave it in a place where it might get too hot (like in a car on a summer day) or cold (like in a garage during winter)

Participants would be randomized to injectable GHK-Cu, to placebo injection, and ideally to a topical GHK-Cu arm for a route comparison

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GHK-Cu (Glycyl-L-Histidyl-L-Lysine-Copper) is a naturally occurring copper-binding tripeptide found in human plasma, saliva, and urine

Ubiquitin-proteasome system enhancement through 41 upregulated genes strengthens cellular quality control, clearing damaged and misfolded proteins