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[10] In dose-ranging studies, tamoxifen was administered at very high doses in women (e.g., 300 mg/m 2 ) and was found to produce acute neurotoxicity including tremor, hyperreflexia, unsteady gait, and dizziness

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To understand the dynamics of myelin changes during CPZ intoxication, we introduced a cohort of animals that experienced both interventions simultaneously for 3 weeks (CPZ plus either 40 Hz or control constant light and sound) (Supplementary Fig