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Research on L-citrulline (which increases glutathione availability through its role in the arginine-nitric oxide cycle) has demonstrated protective effects against kidney damage in various models

PMID 39277120

[DOI] [PubMed] [Google Scholar] 74.Kandarakis S.A., Togka K.A., Doumazos L., Mylona I., Katsimpris A., Petrou P., Kymionis G

These findings underscore the dual role of SNO modification across various cancer types

Further, in a Request for Information in the CY 2023 PFS final rule (87 FR 69977 through 69979), we discussed addressing health equity through benchmarking and summarized related comments

Proposed mechanisms for all these increased risks included systemic low-grade inflammation, alterations in neuronal signaling, particularly dopamine and serotonin signaling pathways, and the influence of UPF additives on neurochemical regulation