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The development of composite materials that are fully biodegradable and whose degradation products (such as specific metal ions) have biobeneficial functions (such as promoting angiogenesis and immune regulation) will achieve a transformation from passive carriers or scaffolds to active microenvironment modulators

doi: 10.1038/s41597-020-0448-0

There is only one very notable exception, though

In summary, both methionine and cysteine metabolism in ECs affect oxidative stress through the involvement of metabolic intermediates (Carter and Morton, 2016