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10.1136/annrheumdis-2016-210942 29 WattsR.LaneS.HanslikT.HauserT.HellmichB.KoldingsnesW.et al (2007)

This review discusses recent clinical and laboratory studies investigating the neuroprotective properties of metformin against DM-induced neurodegeneration and the roles of various molecular pathways, including mitochondrial dysfunction, oxidative stress, inflammation, apoptosis, and its related cascades