mitochondrial glutathione regulation and functions Pleiotropic effects of a mitochondrion-targeted reductase inhibitor on restraining tumor cells what are the roles of

10.1021/acsaenm.4c00176 [DOI] [PMC free article] [PubMed] [Google Scholar] Cao B., Zheng Y., Xi T., Zhang C., Song W., Burugapalli K., et al

Studies have shown that GSTP1 plays a crucial role in maintaining cellular oxidative homeostasis and regulating cell proliferation and apoptosis (Tew et al., 2011)

Neuronal oxidative stress can be caused by a number of cellular mechanisms 29

Therefore, methionine is converted into methionine sulfoxide which is then reconverted to the methionine throughout the oxidation of NADPH (Atmaca 2004

Liposomal Glutathione, on the other hand, uses phospholipid nano-spheres to encapsulate glutathione, protecting it from digestive enzymes and allowing direct absorption into the bloodstream

Aptamers are thermostable and chemically stable, and chemical modification can enable their conjugation to nanoparticles, drugs, or other nucleic acid drugs to improve cellular uptake