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Quantitative variables will be described in terms of their measure of central tendency, mean or median (for those showing asymmetric distributions), and the corresponding dispersion, standard deviation or interquartile range

The honest summary is that long-term human safety data is missing and the angiogenesis mechanism is an unresolved theoretical concern

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Regarding prevention, the British Society of Hematology states that it cannot provide recommendations on the indications for the prophylactic administration of vitamin B12 in patients with T2D treated with metformin [14]