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A larger study (SEMA-NASH) enrolling 320 individuals with obesity, biopsy-proven NASH and different degrees of fibrosis, with or without diabetes, demonstrated that OD subcutaneous semaglutide 0.4 mg significantly resolved MASH without worsening fibrosis in 59% of patients 93

For drawing bacteriostatic water from its vial, a separate larger syringe (3 mL with an 18-22 gauge needle) makes the process faster and more accurate

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The neuroprotective effect is perhaps the most significant because in neurodegenerative diseases such as Alzheimer's disease or Parkinson's disease, it may save cells from deterioration induced by specific agents