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This suggests that the transcription coactivator CRTC2 may be the main factor responsible for the increased miR-93-3p expression

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Toxicol Sci 141, 263277, doi: 10.1093/toxsci/kfu124 (2014)

Upon the activation of oxidative stress, ROS are produced in large quantities, which attract SOD and CAT to neutralize ROS by converting them into H 2 O 2