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10.1016/s0014-2999(00)00542-2 8 AnderssonH.DemaegdtH.JohnssonA.VauquelinG.LindebergG.HallbergM.et al (2011)

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The hippocampus serves as a critical region of interest in this study for two key reasons: once the aforementioned ghrelin-mediated influence on hippocampal neurogenesis and synaptic plasticity, and the established role of the hippocampus in the pathophysiology of major depression 40 , highlighting its relevance to obesity-depression comorbidity