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Tumorigenesis and development Ferroptosis has been reported to either inhibit or promote tumorigenesis in different models

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For instance, the developed CD44v6-CAR T cells demonstrated antitumor effects and significantly prolonged survival (median survival of 27 and 37 days in CD19-CAR and CD44v6-CAR treated groups) of mice with ovarian cancer tumors (Porcellini et al., 2020)