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Description

Animal studies have shown that P140 treatment reduces the clinical and histological severity of colitis in CD-induced mice, suggesting it may serve as a valuable therapeutic target for IBD [104]

Huang, K.-P

Statements Author contributions WL and CL wrote the manuscript

Recent evidence suggests another important function of NO is to regulate intracellular trafficking of vesicles and cargo

The etiology of these symptoms is unknown, however several illness-causing mechanisms have been hypothesized, including microbial persistence, host immune dysregulation through inflammatory or secondary autoimmune pathways, or altered neural networks, as in central sensitization