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The first cells to migrate during the early stages of inflammation are neutrophils, which are controlled by mast cells and macrophages in the tissues

Since ER handles massive proteins, the quality of proteins folded and maturated, and possibly also ER redox state must be strictly controlled 1,2

Preclinical data have shown that resveratrol substantially augments radiosensitization of glioma stem cells in both in vitro and in vivo by inducing autophagy, thus preventing tumorigenesis and tumor recurrence [140]

Exposure to toxic substances disrupts plasma membrane integrity, leading to LDH leakage into the cell medium [30]