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Elevated homocysteine levels can lead to vascular complications, increasing the risk for atherosclerosis and heart disease

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Moreover, these macrocyclic peptides have been observed to downregulate MNAM production in cellular assays

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Kastora SL, Herrero-de-Dios C, Avelar GM, Munro CA, Brown AJP

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Given the important role of humoral immunity in the development of CTD-ILD as signified by the association of certain antibodies with the development of ILD, it was hypothesized that rituximab, an anti-CD20 antibody that depletes B-cells (74), would have a beneficial effect for the treatment of CTD-ILD

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That means long-term risk estimates are uncertain

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Curious to hear thoughts from the low-carb/carnivore community

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