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Viruses were used to infect Vero E6 cells (ATCC CRL-1586) grown in Dulbeccos Modified Eagles Medium (DMEM) (Gibco) supplemented with 1% penicillin/streptomycin (Sigma) and 2% fetal bovine serum (Sigma)

This is one of the most important regulatory enzymes in PQ synthesis, since under exposure of Arabidopsis plants to increased light intensity, an accumulation of PQ was observed accompanied by the increase of transcript levels of the genes encoding the enzymes of plastoquinone biosynthesis and, first of all, the gene encoding SPS1 [48]

Plant Physiol 141:11381148 Opdenakker K, Remans T, Vangronsveld J, Cuypers A (2013) Mitogen-activated protein (MAP) kinases in plant metal stress: regulation and responses in comparison to other biotic and abiotic stresses

With further investigation, nano-carotenoids and particularly nano-lutein could potentially become an effective alternative treatment for patients with FM who do not respond to current treatment options

10.1136/jnnp.2005.083378 J

Further research is thus necessary to establish the exact mechanisms and to provide clear treatment guidelines for lupus patients