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Clinical benefits may include: Protection and growth of lean muscle tissue are critical consideration for patients on GLP-1 weight loss medications

Cardiovascular disease High homocysteine levels are associated with an increased risk of heart disease and stroke as it may promote the formation of blood clots and excess free radical cells, and may impair normal blood vessel function

The increased protein binding of hydroxocobalamin sustains circulating vitamin B12 levels for longer than cyanocobalamin

By directly delivering the vitamin to the bloodstream, they can help to improve energy levels, mood, and cognitive function

In addition to the press releases (which had already been published) I read several of Pfizers references as I tried to drill down into the science

Signs You May Need a Higher B12 Dosage Recognising when current B12 intake or supplementation may be inadequate is important for preventing progression to more serious deficiency states