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Mitochondrial atrophy was observed under transmission electron microscopy 15 minutes after SCI, which is a typical morphological feature of ferroptosis, becoming more obvious one day later

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During these states, our requirements for glutamine increase to a considerable degree, and the amino acid is consumed at a faster rate than it can be produced

After filtration and centrifugation, the cell pellet was resuspended with low glucose Dulbeccos modified Eagles medium (DMEM, Gibco) containing 10% fetal bovine serum (FBS, Gibco) and 1% penicillinstreptomycin (Gibco) at 37 C and 5% CO2 in 10-cm dishes

Lanska of the University of Wisconsin School of Medicine and Public Health has no relevant financial relationships to disclose

This is shown by the silencing of the amygdala-vmPFC neural pathway, which not only impaired the fear extinction formation process but also reduced the activity of the amygdala