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The oxidative stress is the result of the imbalance of the antioxidant system in favor of prooxidants, which interferes with the GSH/GSSG system in the antioxidant defense and the regulation of gene expression, the synthesis of DNA and proteins, cell proliferation and apoptosis, and cytokine production and protein glutathionylation, due to alteration of certain cellular functions

Eur J Med Chem 101:295312 Yilmaz S, nal F, Yzbaolu D, Celik M (2014) DNA damagein human lymphocytes exposed to four food additives in vitro

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