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in: PubMed | Google Scholar | 1 Department of Molecular and Integrative Physiology, 2 Department of Internal Medicine, Division of Gastroenterology, 3 Rogel Cancer Center, and 4 Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, Michigan, USA

Upon bacterial infection, WRS is secreted by the monocytes, and directly binds to macrophages via a toll-like receptor 4 (TLR4)-myeloid differentiation factor 2 (MD2) complex, inducing phagocytosis and chemokine production ( in vitro and in vivo (Lee et al., 2019)

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Anthocyanins (ANT) are polyphenolic substances present in a variety of foods

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So, you cant use the same product all over your face, because they have different issues that need to be addressed