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[DOI] [Google Scholar] 137.Song W., Wei F., Gao S., Dong C., Hao J., Jin L., Li F., Wei P., Guo J., Wang R

The release of TNF-a and IL-1b from dying KCs results in monocyte recruitment to the liver

Obesity increases adipocyte development and cell hypoxia, which stimulates inflammatory chemokines and cytokines via HIF1 in adipose tissue macrophages (ATMs), inducing their polarization into the M1 phenotype (Shi et al., 2006)

Prodrugs are molecules with little pharmacological activity that permit conversion to active native drugs in vivo by chemical or enzymatic reactions

The autophagylysosome pathway is not simple or unidirectional