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Moreover, GLPs suppress NOX4 expression, decrease H 2 O 2 and MDA accumulation, and boost the enzymatic activity of key antioxidantsincluding SOD, CAT, and GSH-Pxthereby mitigating oxidative stress and associated DNA damage

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5.2 DNA methylation The transcriptional regulation of redox-related genes in the retina is influenced by the methylation of cytosine residues in DNA, a critical epigenetic mechanism that responds to environmental changes (119)

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