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However, there are limitations to mouse models including the small size and lack of complexity of the mouse brain ( Statements Data availability statement The raw data supporting the conclusions of this article will be made available by the authors, without undue reservation

There were two experimental treatments: Control diet and the same diet containing zinc oxide at 3,000 mg/kg (ZnO)

Quercetin works by adjusting these transporters to help remove more uric acid

Once activated, peripheral nociceptor neurons release pro-inflammatory mediators that sensitize or activate nearby cells in the injured area (22)(24)

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