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Its pathogenesis was ill understood 45, and its treatment was neglected with the anticipation that the patient would eventually recover, albeit over a period of some 1-2 years and after suffering considerable pain, weakness and disability

Alcohol Clin Exp Res 22(7):15381543 Saini J, Goyal AK, Jangra A (2019) High-fat diet with alcohol elevate oxidative stress which cause hyperlipidemia by inducing mutation in the ANGPTL3 locus

Histologically, they are characterized by large, polygonal cells with clear cytoplasm and thin strands of cytoplasm extending to the cell membrane, known as spider cells