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Sci Transl Med, 2014, 6(231): 231ra247

Lyophilised shelf life is up to 24 months when stored correctly

In addition, the SOCS gene is activated by GH signaling and works as a short intracellular negative feedback loop which rapidly down-regulate GHR activity by internalization and receptor ubiquitinoylation resulting in lysosomal and proteasomal degradation (101)

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**Final Mix:** Continue stirring for another minute, ensuring all ingredients are fully integrated