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The relationships between clinical data, CD activity, plasma and salivary parameters were evaluated using the Spearman's rank correlation coefficient

Most of the studies focused on acetate, propionate, and butyrate, however, the anti-tumor effect of valerate, specifically in NSCLC is poorly understood

This is achieved by stimulating the activity of immune cells, such as M1 macrophages and CD8+ T lymphocytes, and by promoting the secretion of pro-inflammatory cytokines, including interferon-gamma

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By targeting and inducing either ferroptosis or cuproptosis, researchers hope to overcome tumor resistance to conventional treatments