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Other organ system-based : Causes can come from the kidneys (e.g., stones), reproductive system (e.g., ovaries), or gastrointestinal system (e.g., inguinal hernias, appendix)

Endogenous neuroprotection is considered the main direction in solving the problem of combating ischemic damage, the mechanisms of which lead to an increase in the stability of brain cells due to the activation of their own adaptation mechanisms

In addition to systemic toxicity caused by chemotherapy, systemic administration of ADCs can introduce toxicity from the antibody components, inducing immune responses and causing severe secondary injuries that lead to nephrotoxicity in patients 19

J Card Surg, 18(6), 500-503

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We would not expect a close match to the clinically observed percentage changes because we are comparing intracellular model changes to blood measurements